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Two-dimensional nanomaterials, such as graphene and molybdenum disulfide (MoS2), have recently attracted widespread attention as surface-enhanced Raman scattering (SERS) substrates. However, their SERS enhancement is of a smaller magnitude than that of noble metal nanomaterials, and therefore, the detection sensitivity still needs to be substantially improved for practical applications. Here, we present the first detailed studies on the effect of the (MoS2) interlayer distances on the SERS intensity enhancement. We find that MoS2 with

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