https://www.selleckchem.com/pr....oducts/shp099-dihydr
Aim Gene polymorphisms are critical in warfarin dosing variation. Here, the role of rare CYP2C9 alleles on warfarin doses in Chinese Han patients was investigated. Methods A retrospective study recruited 681 warfarin treated atrial fibrillation patients. The genetic and clinical data were collected. Dose-related variables were selected by univariate analyses and the warfarin-dosing algorithm was derived by multivariate regression analysis. Results Three rare CYP2C9 alleles (CYP2C9*13, *16 and *6 were associated with low
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