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We unearthed that 274 genes had been upregulated and 183 genetics had been downregulated. Network analyses on significant DEGs indicated 12 hub genetics associated with HE. Enrichment analysis identified fatty acid beta-oxidation, cerebral natural acidurias, and regulation of actin cytoskeleton as main included pathways connected with upregulated genes; serotonin receptor 2 and ELK-SRF/GATA4 signaling, GPCRs, course A rhodopsin-like, and p38 MAPK signaling pathway had been related to downregulate

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