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Additionally, within the analyses of diploid Hi-C datasets in mouse and individual, our ASHIC-ZIPM strategy produced fine-resolution diploid chromatin maps and 3D structures and supplied insights to the allelic chromatin organizations and procedures. To close out, our work provides a statistically rigorous framework for investigating fine-scale allele-specific chromatin conformations. The ASHIC application is openly readily available at https//github.com/wmalab/ASHIC.TransCirc (