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To date, no anti-viral therapy apart from supporting attention exists. In 2015, the first and only dengue-vaccine, CYD-TDV, obtained marketing authorization. To provide the present knowledge of dengue in terms of epidemiology, transmission, pathogenesis, disease administration and avoidance. To illustrate the knowledge spaces that remain to be filled so that you can get a handle on dengue and achieve the which 2010-2020 objectives. An updated systema

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