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This stimuli-responsive mode not merely eliminates the insulation effect of MOFs but also provides a firm loading method for electroactive dyes. Under the optimal conditions, the proposed immunoassay for SCCA had displayed excellent performance with a wide linear range from 1 µg mL-1 to 1 pg mL-1 and an ultralow detection limit of 1.504 fg mL-1 (S/N = 3) under the optimal conditions.N-doped carbon quantum dots (NCQDs) were synthesized by a hydrothermal method using folic acid and o-phenylenediamine as precursors. The inhibition behaviour o