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ADHD Treatment For Adults stimulants such as amphetamine and methylphenidate increase the levels of certain brain chemicals. Non-stimulants such as atomoxetine and antidepressants are slower than stimulants, but they could be as effective. Complicating conditions can impact the effectiveness to ADHD medications. Physicians should treat the most severe symptom of any comorbid disorder first, and then monitor whether the ADHD symptoms improve. Medication Medication is the most popular treatment option f