https://www.selleckchem.com/pr....oducts/prostaglandin
Interestingly, HPV66E6* which does not promote Dlg degradation can be converted into a form capable of facilitating Dlg degradation through the insertion of nine amino acids (20-28) containing the class III PBM from HPV16E6*. HPV16E6*-induced Dlg degradation appeared independent of E6AP. The internal class III PBM of HPV16E6*I required for Dlg degradation is identified. This study highlights that a novel class III PBM as the domain responsible for Dlg degradation activity in high-risk HPVE6*. This study highlights that
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