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Forty-two rats were divided into non-ovariectomized ( NO ) and ovariectomized ( O ) groups , separated into three subgroups : restraint ( empty mar ) and two subgroups meeting collagen/chitosan/hydroxyapatite scaffolds machinated using dissimilar methods of hydroxyapatite incorporation , in situ ( CoChHa1 ) and ex situ ( CoChHa2 ) . The defect arenas were submitted to macroscopic , radiological , and histomorphometric psychoanalysis . No instigative processes were incured in the tibial defect area that would show resista
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