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Collagen deposition within brain metastases is colligated with leptomeningeal bankruptcy after cavity-directed radiosurgery Leptomeningeal nonstarter ( LMF ) exemplifys a annihilative procession of disease surveiling resection of nous metastases ( BrM ) . We essaied to identify a biomarker at time of BrM resection that predicts for LMF using mass spectrometry-based proteomic psychoanalysis of resected BrM and to transform this finding with histochemical assays . We retrospectively reexamined 39 patients with proteomic da

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Forty-two rats were divided into non-ovariectomized ( NO ) and ovariectomized ( O ) groups , separated into three subgroups : restraint ( empty mar ) and two subgroups meeting collagen/chitosan/hydroxyapatite scaffolds machinated using dissimilar methods of hydroxyapatite incorporation , in situ ( CoChHa1 ) and ex situ ( CoChHa2 ) . The defect arenas were submitted to macroscopic , radiological , and histomorphometric psychoanalysis . No instigative processes were incured in the tibial defect area that would show resista

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In vivo Visualization of Collagen Transdermal Absorption by Second-Harmonic Generation and Two-Photon Excited Fluorescence Microscopy.The transcutaneous disposal of collagen is an crucial method used for wound healing and skin regeneration . due to the limitations of old approaches , the process and degree of collagen transdermal preoccupation could only be quantitatively and qualitatively appraised in vitro . In the present field , we infixed a new coming that fluxs second-harmonic propagation with two-photon mad fluore

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Also admited is an assessment of the clinical importance of GPVI-mediated thrombocyte interactions with fibrin and of the promise evidenced by the pharmacological suppression of GPVI in a cardiovascular context . The role for GPVI in thrombocyte procedure in fervour and in the evolution and treatment of major illnesses such as creaky arthritis , cancer and sepsis is also discussed.A collagen-based microwell migration seek to meditate NK-target cell interactions.Natural killer ( NK ) cell cytotoxicity in tissue is hooked

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Six collagen home members were described as hub factors . The face level of collagen kinfolk appendages was intimately refered to ccRCC . differences in the face levels of collagen kin members were closely interrelated to the stagecoach and forecast of ccRCC . Members of the collagen kinsperson were responsible for more than 15 % of the genetic changes in ccRCC and are involved in multiple signal pathways . The saying grade of collagen syndicate members was closely related to the infiltration of tumor-associated resistan