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03) and superotemporal (p=0.04) sectors. A higher proportion of significant negative rates was observed with Spectralis OCT both globally and in inferotemporal/superotemporal sectors (p0.04). Permutation analyses confirmed the higher proportion of global and sectoral negative rates of change with Spectralis OCT (p0.001). Changes in macular GCIPL were detected more frequently on Spectralis' longitudinal volume scans than those of Cirrus OCT. OCT devices are not interchangeable with regard to detection of macular structural progre

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