https://www.selleckchem.com/pr....oducts/oicr-9429.htm
We found that DU145 cells treated with HPRT antibodies had a significantly higher incidence of cell death than both isotype treated samples and PC3 cells treated with the same concentrations of HPRT antibody. Finally, we determined that p53 had a significant impact on HPRT expression both internally and on the surface of cancer cells. These results suggest HPRT as a possible biomarker target for the treatment of patients with prostate cancer. Recent literature has shown an association between atherosclerotic cardiovascular disease and
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