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and attitude of doctors, nurses and patients. The findings from this study can be used to develop and implement interventions for venous thromboembolism after orthopaedic surgery. The findings from this study can be used to develop and implement interventions for venous thromboembolism after orthopaedic surgery. HTL0018318 is a selective M receptor partial agonist currently under development for the symptomatic treatment of cognitive and behavioural symptoms in Alzheimer's disease and other dementias. We investigated safety, tolerabilit