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ADHD Medication Medication can help adults and children focus better, relax and manage their impulses. The majority of people with ADHD report that their symptoms improve after taking medication. The most commonly prescribed drugs for ADHD work by increasing levels of dopamine and norepinephrine in the brain. These medications are available as immediate-release tablets (2 to 3 small doses, taken twice daily), or as long-acting, extended-release formulas which build up in the body f