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To assess the impact of socio-economic deprivation on endometrial cancer survival. Single-centre prospective database study. North West England. Women with endometrial cancer treated between 2010 and 2015. Areal-level socio-economic status, using the English indices of multiple deprivation from residential postcodes, was analysed in relation to survival using Kaplan-Meier estimation and multivariable Cox regression. Overall survival, cancer-specific survival and patterns and rates of recurrence. A total of 539 women, with a median age o