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Our studies in an immunocompetent preclinical mouse model demonstrate TAMs can have a functional role in promoting SHH-MB progression. Thus, CSF1R inhibition could have therapeutic potential for a subset of SHH-MB patients.Samples of South African bituminous coals were analysed for total mercury (Hg) and Hg thermospecies concentrations using an RA-915 + Zeeman Mercury Analyser. Total mercury concentrations in samples of coals (n = 57) ranged between 10 ng g-1 and 493 ng g-1 with a mean value of 150 ± 53 ng g-1. Thermospecies of Hg were