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Recently, more evidences manifest that the subjective cognitive decline (SCD) of unimpaired individual may represent first symptom of Alzheimer's disease (AD). This study investigated the differences of intrinsic glucose metabolic functional connectivity between SCD and healthy subject (HC) groups from the perspective of brain network topology. In this study we attained 18F-Fluorodeoxyglucose positron emission tomography (18F-FDG PET) scans from Xuanwu Hospital, Beijing, China, including 85 SCD subjects (male = 16, mean age = 66, MMSE = 2
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