https://www.selleckchem.com/pr....oducts/nsc-23766.htm
43 years), with the others remaining static or decreasing in size in the absence of any cytotoxic therapy. Targeted smMIPS sequencing can sensitively measure clonal dynamics in CHIP. Mutations that reached the conventional threshold for CHIP (2% frequency) tended to continue growing, indicating that after CHIP is acquired, it is generally not lost. The ability to cost-effectively profile CHIP longitudinally will enable future studies to investigate why some CHIP clones expand, and how their dynamics relate to health outcomes at a biob
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