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Finding the Best ADHD Medication For Adults Medications are the cornerstone of a variety of adult ADHD treatment plans for adults with ADHD. Finding the right medication dosage and dose isn't always easy. Stimulants: These medicines are used to treat hyperactivity and inattention. They work by increasing the levels of brain chemicals that transmit messages between nerve cells. They are taken several times per day and begin working in less than one hour. a