https://www.selleckchem.com/pr....oducts/Staurosporine
To examine the role age plays in the treatment and prognosis of locally advanced head and neck cancer (LAHNC) treated definitively with radiation alone or combined modality therapy. A retrospective analysis was performed of three NRG/RTOG trials examining either radiation alone or combined radiation and systemic therapy for LAHNC. The effect of age (≥70 yrs.) on cause-specific survival (CSS), overall survival (OS), and toxicity was evaluated. A total of 2688 patients were analyzed, of whom 309 patients (11.5%) were ≥ 70. For all s