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Dear Editor, Findings from nationally representative health databases have been shown to influence management guidelines and research spending.1 However, conclusions drawn from national datasets require disease validation. Cutaneous adverse drug reactions are one of the most common dermatologic findings in the hospital setting and in general with antibiotic exposure, yet most forms lack support to demonstrate diagnosis code validity. Deformable image registration (DIR) of lung four-dimensional computed tomography (4DCT) plays a vital ro