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Moreover, two types of ventilator dyssynchrony, double-triggered and flow-limited breaths, are associated with the more frequent delivery of large tidal volumes 10 mL/kg when compared with synchronous breaths (54% [95% confidence interval (CI), 47%-61%] and 11% [95% CI, 7%-15%]) compared with 0.9% (95% CI, 0.0%-1.9%), suggesting a role in propagating VILI. Finally, a recent study associated frequent dyssynchrony-defined as 10% of all breaths-with an increase in hospital mortality (67 vs. 23%, P = 0.04). However, the clinical signif
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