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istic regression analysis. The volume of the PBM of patients treated with concurrent chemoradiotherapy and subjected to both low-dose (V ) and high-dose (V and V ) irradiation was associated with hematological toxicity, depending on the fractional volumes receiving the variable degree of dosage. The NTCP were stronger predictors of toxicity than V , V , and V . Hence, avoiding radiation hot spots on the PBM could reduce the incidence of severe HT. The volume of the PBM of patients treated with concurrent chemoradiotherapy and subjected to