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The sensitivity was 83% (64%-93%) and specificity 98% (80%-100%) when ROSE was available and 65% (57%-73%) and 94% (31%-100%) when not available. The number-needed-to-diagnose was 1.2 (1.1-2.3) and 1.7 (1.4-8.3) in ROSE+ and ROSE- cases, respectively. The number of correctly diagnosed cases increased from 6 (1-7) to 8 (4-9) out of 10 patients without and with ROSE, respectively. CONCLUSIONS This study objectively substantiated the added value of rEUS-FNA for the diagnosis of solid pancreatic masses, in case of a previous nondiagnostic or