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The quality of the data was reasonable (65.8%) to high (34.2%). Additional analysis in bigger samples will become necessary.Hydrogen sulfide (H2S) is considered as a novel second-messenger molecule associated with the modulation of numerous physiological and pathological procedures. In the field of antitumor research, endogenous H2S induces angiogenesis, accelerates the mobile cycle and prevents apoptosis, which results in promoting oncogenesis ultimately. Interestingly, large concentrations