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Aging is generally associated with a cognitive drop and a susceptibility to neuronal harm. Additionally it is the main threat factor for neurodegenerative problems, specially Alzheimer's infection (AD). advertisement is related to an excess of neurotoxic oligomers of amyloid β peptide (Aβo); nevertheless, the molecular components remain very controversial. Intracellular Ca2+ homeostasis plays a crucial role into the control over neuronal activity, including neurotransmitter r