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Opioid abuse remains a significant public health problem. The pseudoirreversible mu opioid receptor antagonist methocinnamox (MCAM) may be useful for treating opioid abuse and overdose. Because endogenous opioid methods can modulate cognition and decision-making, you should evaluate whether long-lasting blockade of mu opioid receptors by MCAM adversely impacts complex operant behavior involving memory. This research tested the results of MCAM in rhesus monkeys responding under a dela