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Three tests, with 265 clients, had been selected for the analysis. OCA had been exceptional to placebo in PBC patients (RR, 1.48; 95% CI, 1.15-1.9. OCA's pooled therapy response rate ended up being 65% (95% CI, 56%-74%), corresponding to Paris I criteria. Besides, OCA significantly reduced complete cholesterol ( This meta-analysis demonstrated that OCA was an encouraging additional treatment plan for PBC clients and could reduce serum levels of cholesterol.