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5%) cases. Analyzed molecular factors had no impact on PFS and OS. Despite accumulation of several poor prognostic factors in our real-life cohort of heavily pretreated patients with CLL, ibrutinib treatment showed long-term clinical benefit. Despite accumulation of several poor prognostic factors in our real-life cohort of heavily pretreated patients with CLL, ibrutinib treatment showed long-term clinical benefit.Major sensory innervation to the uterus is provided by spinal afferent nerves, whose cell bodies lie predominantly in thoracol