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05). At higher programmed DNa (140-145 mEq/L), measured DNa was greater for the BB and F4008 machines by all methods (P 0.05), but only by ISE for the F5008 (P 0.05). We noted a systematic bias in DNa delivery with measured DNa being greater than that programmed by our HD machines. The magnitude of the bias varied between machines and with DNa. Our results may help explain the diverse results reported in studies of DNa. We noted a systematic bias in DNa delivery with measured DNa being greater than that programmed by our HD mach