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After grouping by total chemotherapy cycle (TCC), affects of COD on negative effects and customers' survivals had been examined in each team. Univariate and multivariate success analyses were performed through Kaplan-Meier strategy and COX proportional dangers model, correspondingly. Age, gender, anemia, differentiation, carcinoembryonic antigen, carb antigen 19-9, pretreatment clinical stage and postsurgical pathologic phase were utilized as covariates.