https://www.selleckchem.com/pr....oducts/danirixin.htm
Conventional wisdom posits that aqueous humor leaves the eye by passive bulk flow without involving energy-dependent processes. However, recent studies have shown that active processes, such as cell contractility, contribute to outflow regulation. Here, we examine whether inhibiting cellular metabolism affects outflow facility in mice. We measured outflow facility in paired enucleated eyes from C57BL/6J mice using iPerfusion. We had three Experimental Sets ES1, perfused at 35°C versus 22°C; ES2, perfused with metabolic inhibitors vers