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No systematic review and (or) meta-analysis has been conducted so far to study the effect of gum consumption on anthropometric indices and blood pressure. Thus, our objective was to conduct a systematic review and meta-analysis of the randomized controlled trials investigating the effect of gum consumption on anthropometric indices and cardiac disorders. The literature search was implemented in the Scopus, Web of Science, PubMed/Medline and Google Scholar databases to discover trials that investigated the impact of gum on obesity indices