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ive craniectomy is advised to ensure patient safety and avoid possible morbidities and mortality. Acute brain injuries are associated with high mortality rates andpoorlong-term functional outcomes. Measurement of cerebrospinal fluid (CSF) biomarkersinpatients with acute brain injuriesmayhelp elucidatesome of the pathophysiological pathways involvedin the prognosisofthese patients. We performed a systematic search and descriptive review using the MEDLINE database and the PubMed interface from inception up to June 29, 2021, to retrieve ob
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