https://www.selleckchem.com/pr....oducts/imidazole-ket
Baicalin remarkably inhibited the production of IL-1, IL-18, mitochondria ROS, total ROS, ICAM-1, and VCAM-1. Baicalin reduced the expression of NLRP3 inflammasome and suppressed its activation. Baicalin significantly reduced the plaque area. Silencing NLRP3 resulted in decreased production of IL-1, IL-18, mitochondria ROS, total ROS, ICAM-1, and VCAM-1, and inhibition of NLRP3 inflammasome activation. Baicalin ameliorated atherosclerosis by inhibiting NLRP3 inflammasome. Baicalin ameliorated atherosclerosis by inhibiti