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, acarbose). A bio-guided fractionation strategy had been followed to separate and determine the energetic fractions/compounds of Eucalyptus radiata and Myristica fragrans EOs. The bio-guided fractionation revealed that EOs α-amylase inhibitory activity is usually caused by antagonist, additive, or synergistic interactions among all of their bioactive constituents and led to the recognition of 1,8-cineole, 4-terpineol, α-terpineol, α-pinene, and β-pinene as bioactive substances, additionally co