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SUMO has actually a vital part into the signaling pathway regulating type I interferon (IFN) production, and among the SUMOylation substrates are numerous IFN-induced proteins. The entire effectation of IFN is increasing worldwide SUMOylation, pointing to SUMO included in the antiviral tension response. Viral representatives are suffering from various systems to counteract the antiviral tasks exerted by SUMO, and some viruses have developed to take advantage of the host SUMOylation equi
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