https://www.selleckchem.com/pr....oducts/ly3023414.htm
The blood-brain barrier is the most important barrier in the entire organism and the skin separates the human body from the environment.Thrombolytic therapy with recombinant tissue plasminogen activator (rtPA) in ischaemic stroke has been associated with neurotoxicity, blood brain barrier (BB disruption and intra-cerebral hemorrhage. To examine rtPA cellular toxicity we investigated the effects of rtPA on cell viability in neuronal, astrocyte and brain endothelial cell (bEnd.3) cultures with and without prior exposure to oxygen-gluc
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