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Therefore, the indirect path of the present model (including tiredness of voice to VRQOL through DSI, physical discomfort to VRQOL through DSI and the improvement of symptoms with rest to VRQOL through DSI) did not show a significant relationship. The vocal fatigue directly affects VRQOL. However, it does not affect it indirectly through DSI. Therefore, it can be concluded that although DSI and VRQOL are correlated, they do not have a causal relationship and DSI, as an acoustic parameter, cannot be an appropriate mediator for th