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The purpose of this study was to evaluate the sensitivity of a tobacco use screening question, modified to include the word "e-cigarette," in detecting past 12-month nicotine vaping and past 12-month tobacco product use inclusive of nicotine vaping, among adolescent primary care patients. We conducted secondary analysis of data from a pilot trial of adolescent substance usescreening and brief intervention in pediatric primary care. Participants were patients aged 12-18years (N= 278) presenting for annual well-visits at five practices i