https://calciumchannelsignals.....com/index.php/an-air
Here we report that MAFB knockout hPSCs have actually typical pancreatic differentiation ability as much as the progenitor phase, but favor somatostatin- and pancreatic polypeptide-positive cells at the cost of insulin- and glucagon-producing cells during endocrine cellular development. Our results describe a requirement for MAFB later within the individual pancreatic developmental program and recognize it as a distinguishing transcription factor within islet cell subtype sp
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