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What Happens If ADHD is Left Untreated in Adults? Adults suffering from ADHD can experience a range of issues if the condition is not treated. These can include issues with work, relationships and mental health. Adults who suffer from untreated ADHD typically have low self-esteem and have a negative outlook on the world. This can cause them to feel like they are failing both at work and at home. Inattention and lack of Focus It is normal to have difficulty focusing from time to time especially