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This case report features diagnostic and therapeutic strategies for primary cutaneous B-Cell lymphoma-leg type. Cancer is recognized as one of the deadliest human conditions these days. Angiogenesis, the propagation of new arteries from pre-existing vasculature, is a crucial step up the development of cancer tumors because it's crucial in the growth and metastasis of tumors. Hence, suppression of angiogenesis is a promising approach in disease treatment. Syringin, a