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OBJECTIVE Vasospasm after subarachnoid hemorrhage (SAH) plays a vital role in the development of delayed cerebral ischemia. Anti-VEGF antibodies, like bevacizumab, may attenuate VEGF- stimulated angiogenesis, reduced vascular cell proliferation, and improve vasospasm after SAH. METHODS Thirty-two adult male New Zealand white rabbits were randomly divided into four groups of eight rabbits in each group group 1 (control); group 2 (subarachnoid hemorrhage); group 3 (subarachnoid hemorrhage + vehicle); and group 4 (subarachnoid hemorrhage