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In addition to ecological S. uberis IMI, at the least 3 types of infectious IMI S. uberis can be explained as (1) short period of IMI and very likely to have spontaneous cure, (2) long duration and unlikely having spontaneous cure, and (3) wide range of extent of IMI either transient or persistent where spontaneous remedy might occur based on host defense capacity. While CYP2D6 allele and phenotype frequencies are thoroughly stu