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Treatment of Add in Adults Treatment of Add in adults usually involves a combination of medication, life-skills training and psychotherapy. Most patients respond to stimulant drugs like methylphenidate, (Ritalin), and amphetamines such as Lisdexamphetamine (Adderall XR) or extended-release mixed amphetamine salts. The effects of stimulants can increase blood pressure and heart rate. Non-stimulants such as atomoxetine, bupropion can also help to improve ADH