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Moreover, we also proved that Treg cells were not involved in the protective effect of IL-9, and meanwhile, CD4 CD25 T cells secreted more IFN-γ and less IL-17A in vitro due to the deletion of Il9. IL-9 plays a protective role against H.pylori and the protection associated with cytokines change including IFN-γ and IL-17A. IL-9 plays a protective role against H. pylori and the protection associated with cytokines change including IFN-γ and IL-17A.CD163 is one of the scavenger receptors expressed on macrophages. However, several immunohis