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No obvious abnormalities in the hematology analyses, blood biochemistry, or histological examinations were observed during the treatment. We successfully engineered a nanocarrier coloaded with the radionuclide I and a photosensitizer precursor for combined radiotherapy and PDT for the treatment of breast cancer. We successfully engineered a nanocarrier coloaded with the radionuclide 131I and a photosensitizer precursor for combined radiotherapy and PDT for the treatment of breast cancer. Coats disease is a retinal vascular disorder charac