https://www.selleckchem.com/pr....oducts/pnd-1186-vs-4
A linear effect of dose and a significant influence of weight and renal function in plasmatic levels of vancomycin was observed. The results of this work corroborate the accumulation of vancomycin in plasma and identify some parameters that influence the pharmacokinetics of this antibiotic. The importance of therapeutic monitoring of vancomycin is highlighted, and the usefulness of in silico tools, namely PBPK modeling, is demonstrated. The results of this work corroborate the accumulation of vancomycin in plasma and identify s
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