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This clinical report describes the treatment of a patient with a large defect area in the maxillary central incisor, left lateral incisor, canine, and first premolar area after a partial maxillectomy. Computer-aided design and computer-aided manufacturing (CAD-CAM) techniques including rapid prototyping and milling were applied together to fabricate a removable partial denture. Although studies have reported on selective laser melting (SLM)-fabricated removable partial dentures (RPDs), research addressing the trueness of SLM-fabricated